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KMID : 1143420170100080179
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Public Health Weekly Report
2017 Volume.10 No. 8 p.179 ~ p.184
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The Prevalence and Characteristics of Bacillus cereus in Korea, 2012-2015
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Jung Su-Mi
Kim Nan-Ok
Hong Kyu-Rak
Kang Byung-Hak
Kwak Hyo-Sun
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Abstract
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BACKGROUND: The bacteria Bacillus cereus is widely present in nature and has the ability to survive in harsh environments. B. cereus causes two types of gastrointestinal diseases: emesis and diarrhea. It produces one emetic toxin (cereulide) and several enterotoxins (entFM, nheA, cytK2, hblC and bceT). We investigated the prevalence and toxin type characteristics of enterotoxic and emetic Bacillus cereus isolated from the laboratory surveillance system in Korea from 2012 to 2015.
METHODOLOGY: A total of 900 B. cereus strains were collected by the National Research Institute of Health (NIH) laboratory surveillance system from 2012 to 2015. Collected strains were analyzed according to isolated season and patient age. Additionally, the presence of enterotoxic and emetic toxin genes was analyzed.
RESULTS:The isolation rate of B. cereus strains increased during the summer, and the ages of positive cases were highest from those 60 to 69 years old. 80.2% of B. cereus have enterotoxin genes (enterotoxic strain) and 19.8% have enterotoxin and emetic toxin genes (emetic strain). The prevalence of five enterotoxin genes (entFM, nheA, cytK2, hblC, and bceT) amongst enterotoxic strains was 89.1%, 82%, 51.8%, 45.8%, and 41.4%, respectively, and prevalence in emetic strains was 78.7%, 59.0%, 14.6%, 9.0%, and 11.2%, respectively. Thus, distribution of the five enterotoxin genes was lower in emetic B. cereus.
CONCLUSIONS: Based from the results, the prevalence of enterotoxin genes was lower in emetic strains as compared to enterotoxic strains. Specifically, entFM and nheA genes were the major enterotoxin genes found in both enterotoxic and emetic strains isolated in Korea. The prevalence of cytK2, hblC, and bceT genes was low in emetic strains.
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KEYWORD
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